News and Events


News

Development of tools for measuring protein concentrations in saliva

Oct 27 2016

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Launching highly-multiplexed MRM-MS services

Jul 08 2016

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Developing proteomics-based tools for patient selection for clinical trials

2016

Partners: Partners: AstraZeneca, UVic, McGill

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Clinical Applications of MALDI-TO

2016

Partners: Partners: Bruker

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Development of proteomics tools including 97-protein panel for dried blood spots

Sep 18 2015

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Distribution & marketing partnership with Cambridge Isotope Laboratories:

2015

Partners: Partners: Bruker

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Part of the fastest growing research economy in Canada

2015

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Marketing partnership with Agilent Technologies

Jul 24 2014

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Launching kits for SCIEX 6500 MS

May 15 2014

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Developing mouse proteomics tools to support drug development

2014

Partners: UVic

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Evolution of Mass Spec & Proteomic

Nov 15 2013

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Launching first kits for Quality Control of MRM-MS proteomics workflows

Oct 09 2013

Partners: Bruker

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Developing blood-based tests for Muscular Dystrophy

2013

Partners: Partners: PROOF, Jain Foundation

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Developing blood tests for chronic disease diagnosis

Sep 26 2012

Partners: PROOF

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Clinical Applications of targeted MRM-MS

Sep 21 2012

Partners: Agilent

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Events Calendar


Upcoming

September 2018

23-26

September

International Congress on Personalized Healthcare 2018

Montreal, QC

30

September

03

October

World HUPO 2018

Orlando, FL

October 2018

16-19

October

MRM Proteomics Hands-On Workshop

Montreal, QC


Past

June 2018

26-29

June

MRM Proteomics Hands-On Workshop

Montreal, QC

24-28

June

Metabolomics 2018

Table #5

Seattle, WA

18-21

June

World Preclinical Congress 2018

Booth #309

Boston, MA

11-12

June

Biomarkers and Immuno-Oncology World Congress 2018

Booth #36

Boston, MA

03-07

June

ASMS 2018

Booth #1122

San Diego, CA

April 2018

15-18

April

AACR 2018

Booth #3840

Chicago, IL

February 2018

12-14

February

Molecular Medicine Tri-Con 2018

Booth #208

San Francisco, CA

January 2018

23-25

January

MSACL 2018 US

Booth #21

Palm Springs, CA

November 2017

23-26

November

CONFER 2017

Iasi, Romania

October 2017

26-27

October

Companion Diagnostics (CDx) in Oncology & Beyond

Vienna, Austria

19

October

CFABS – Post-ASMS Meeting

Booth #11

Vancouver, Canada

17

October

CFABS – Post-ASMS Meeting

Booth #03

Montreal, Canada

16

October

CFABS – Post-ASMS Meeting

Booth #16

Toronto, Canada

September 2017

17-20

September

WORLD HUPO 2017

Dublin, Ireland

13-15

September

MRM-MS WORKSHOP

Sponsor

Dortmund, Germany

10-14

September

MSACL EU 2017

Booth #10

Salzburg, Austria

July 2017

17-18

July

Cascadia

Sponsor

Seattle, WA

02-08

July

3rd IMSS / 11th MSBM

Sponsor

Dubrovnik, Croatia

June 2017

26-27

June

9th Worldwide Innovation Network Symposium

Exhibitor, Booth #1

Paris, France

12-16

June

World Preclinical Congress

Exhibitor, Booth #601

Boston, MA

04-08

June

ASMS 2017

Booth #827

Indianapolis, IN

May 2017

04

May

Spring Mass Spec Group Meeting

Booth #12

Toronto, Canada

April 2017

18-20

April

CNPN 2017

Sponsor

Toronto, Canada


Selected Publications

Mar

2018

Nucleic Acids Research

The prolyl isomerase FKBP25 regulates microtubule polymerization impacting cell cycle progression and genomic stability

Dilworth D, Gudavicius G, Xu X, Boyce AK, O’Sullivan C, Serpa JJ, Bilenky M, Petrochenko EV, Borchers CH, Hirst M, Swayne LA, Howard P, Nelson CJ.

Mar

2018

PROTEOMICS – Clinical Applications

Feb

2018

Liver International

Comprehensive bile acid profiling in hereditary intrahepatic cholestasis: Genetic and clinical correlations.

Liu T, Wang RX, Han J, Hao CZ, Qiu YL, Yan YY, Li LT, Wang NL, Gong JY, Lu Y, Zhang MH, Xie CB, Yang JC, You YJ, Li JQ, Knisely AS, Borchers CH, Ling V, Wang JS.

Feb

2018

Clinical Chemistry

Short-term stabilities of 21 amino acids in dried blood spots

Han J, Higgins R, Lim MD, Lin K, Yang J, Borchers CH

Feb

2018

Biomarkers

Verification of a proteomic biomarker panel to diagnose minor stroke and transient ischaemic attack: phase 1 of SpecTRA, a large scale translational study

Penn AM, Bibok MB, Saly VK, Coutts SB, Lesperance ML, Balshaw RF, Votova K, Croteau NS, Trivedi A, Jackson AM, Hegedus J, Klourfeld E, Yu AYX, Zerna C, Borchers CH

Jan

2018

Analytical Chemistry

Top-down hydrogen-deuterium exchange analysis of protein structures using ultraviolet photodissociation (UVPD)

Brodie NI, Huguet R, Zhang T, Viner R, Zabrouskov V, Pan J, Petrotchenko EV, Borchers CH.

Jan

2018

Journal of Proteome Research

Jan

2018

PROTEOMICS – Clinical Applications

An MRM-Based Cytokeratin Marker Assay as a Tool for Cancer Studies: Application to Lung-Cancer Pleural Effusions

Perzanowska A, Fatalska A, Wojtas G, Lewandowicz A, Michalak A, Krasowski G, Borchers CH, Dadlez M, Domanski D

Dec

2017

Blood

Systemic Biomarkers Show Elevated Oxidative Stress and Chronic Inflammation in Two Disorders of Neurodegeneration with Brain Iron Accumulation (NBIA).

Minkley M, Sweeters N, Kasravi S, Ferguson J, Higa A, Jackson A, Smith D, Borchers C, Nashmi R, Macleod P, Neumayr LD.

Sep

2017

Journal of Proteomics

Sep

2017

Nucleic Acids Research

The basic tilted helix bundle domain of the prolyl isomerase FKBP25 is a novel double-stranded RNA binding module.

Dilworth D, Upadhyay SK, Bonnafous P, Edoo AB, Bourbigot S, Pesek-Jardim F, Gudavicius G, Serpa JJ, Petrotchenko EV, Borchers CH, Nelson CJ.

Sep

2017

Analytical Chemistry

Immuno-Matrix-Assisted Laser Desorption/Ionization Assays for Quantifying AKT1 and AKT2 in Breast and Colorectal Cancer Cell Lines and Tumors

Popp R, Li H, LeBlanc A, Mohammed Y, Aguilar-Mahecha A, Chambers AG, Lan C, Poetz O, Basik M, Batist G, Borchers CH

Aug

2017

Journal of Visualized Experiments: JOVE

Peptide and Protein Quantification Using Automated Immuno-MALDI (iMALDI).

Li H, Popp R, Frohlich B, Chen MX, Borchers CH.

Aug

2017

Scientific Reports

Protein expression changes caused by spaceflight as measured for 18 Russian cosmonauts.

Larina I, Percy AJ, Yang J, Borchers CH, Nosovsky A, Grigoriev A, Nikolaev E

Aug

2017

Scientific Reports

Peptide biomarkers used for the selective breeding of a complex polygenic trait in honey bees

Guarna MM, Hoover SE, Huxter E, Higo H, Moon KM, Domanski D, Bixby ME, Melathopoulos AP, Ibrahim A, Peirson M, Desai S, Micholson D, White R, Borchers CB, Currie RW, Pernal SF, Foster LJ

Jul

2017

Science Advances

Jun

2017

Journal of Proteome Research

Multiplexed MRM-based protein quantitation using two different stable isotope-labeled peptide Isotopologues for calibration

LeBlanc A, Michaud SA, Percy AJ, Hardie DB, Yang J, Sinclair NJ, Proudfoot JI, Pistawka A, Smith DS, Borchers CH.

Jun

2017

Journal of Neurotrauma

A targeted proteomics analysis of cerebrospinal fluid after acute human spinal cord injury

Streijger F, Skinnider MA, Rogalski JC, Balshaw R, Shannon CP, Prudova A, Belanger L, Ritchie L, Tsang A, Christie S, Parent S, Mac-Thiong JM, Bailey C, Urquhart J, Ailon T, Paquette S, Boyd M, Street J, Fisher CG, Dvorak MF, Borchers CH, Foster LJ, Kwon BK

Jun

2017

Blood Advances

Multiplexed targeted proteomic assay to assess coagulation factor concentrations and thrombosis-associated cancer

Mohammed Y, van Vlijmen BJ, Yang J, Percy AJ, Palmblad M, Borchers CH, Rosendaal FR.

May

2017

Hepatology

Defects in myosin VB are associated with a spectrum of previously undiagnosed low y-glutamyltransferase cholestasis

Qiu YL, Gong JY, Feng JY, Wang RX, Han J, Liu T, Lu Y, Li LT, Zhang MH, Sheps JA, Wang NL, Yan YY, Li JQ, Chen L, Borchers CH, Sipos B, Knisely AS, Ling V, Xing QH, Wang JS

May

2017

TrAC Trends in Analytical Chemistry

May

2017

Journal of Mass Spectrometry

Current trends in quantitative proteomics–an update

Li H, Han J, Pan J, Liu T, Parker CE, Borchers CH.

May

2017

United States Patent Application

Apr

2017

The Journal of Infectious Diseases

Enteric helminths promote Salmonella coinfection by altering the intestinal metabolome

Reynolds LA, Redpath SA, Yurist-Doutsch S, Gill N, Brown EM, van der Heijden J, Brosschot TP, Han J, Marshall NC, Woodward SE, Valdez Y, Borchers CH, Perona-Wright G, Finlay BB.

Mar

2017

Analytical Chemistry

Mar

2017

Journal of Clinical Microbiology

Mar

2017

Molecular & Cellular Proteomics

New guidelines for publication of manuscripts describing development and application of targeted mass spectrometry measurements of peptides and proteins

Abbatiello S, Ackermann BL, Borchers C, Bradshaw RA, Carr SA, Chalkley R, Choi M, Deutsch E, Domon B, Hoofnagle AN, Keshishian H, Kuhn E, Liebler DC, MacCoss M, MacLean B, Mani DR, Neubert H, Smith D, Vitek O, Zimmerman L.

Feb

2017

Proteomics: Methods and Protocols

Dec

2016

Biochimica et Biophysica Acta (BBA) – Proteins & Proteomics

Dec

2016

Proteomics

PeptideTracker: A knowledge base for collecting and storing information on protein concentrations in biological tissues.

Mohammed Y, Bhowmick P, Smith DS, Domanski D, Jackson AM, Michaud SA, Malchow S, Percy AJ, Chambers AG, Palmer A, Zhang S.

Dec

2016

Springer International Publishing

Protocol for Standardizing High-to-Moderate Abundance Protein Biomarker Assessments Through an MRM-with-Standard-Peptides Quantitative Approach.

Percy AJ, Michaud SA, Jardim A, Sinclair NJ, Zhang S, Mohammed Y, Palmer AL, Hardie DB, Yang J, LeBlanc AM, Borchers CH.

Oct

2016

Proteomics

Multiplexed panel of precisely quantified salivary proteins for biomarker assessment.

Percy AJ, Hardie DB, Jardim A, Yang J, Elliott MH, Zhang S, Mohammed Y, Borchers CH.

Sep

2016

Proteomics

Multiplexed MRM-based assays for the quantitation of proteins in mouse plasma and heart tissue.

Percy AJ, Michaud SA, Jardim A, Sinclair NJ, Zhang S, Mohammed Y, Palmer AL, Hardie DB, Yang J, LeBlanc AM, Borchers CH.

Dec

2015

Future Science

Absolute quantification of 35 plasma biomarkers in human saliva using targeted MS

Hirtz, C, Vialaret J, Nowak N, Gabelle A, Deville de Périère D, Lehmann S.

Sep

2015

EuPA Open Proteomics

Inter-laboratory evaluation of instrument platforms and experimental workflows for quantitative accuracy and reproducibility assessment.

Percy AJ, Tamura-Wells J, Albar JP, Aloria K, Amirkhani A, Araujo GD, Arizmendi JM, Blanco FJ, Canals F, Cho JY, Colomé-Calls N.

2015

Inflammatory Pathways in Diabetes

Jun

2014

Journal of Proteome Research

Dec

2013

Expert Review of Proteomics